Polynucleotides work on skin repair and are one of the few options with real evidence behind them for the delicate under-eye area. They suit dark hollows, crepey texture and thin skin where filler would be the wrong choice. Treatment is a short course spaced a few weeks apart. We will tell you honestly at consultation whether your under-eye concern is a skin issue or a volume issue, because the answer changes the treatment entirely.
Signs You Need Polynucleotides
The clearest sign is dark hollows under the eyes that do not improve with sleep or skincare. The skin there looks thin, crepey or shadowed, and concealer does not fully hide it. This is a skin-quality issue, not a volume issue — and filler placed into thin, dark under-eye skin often makes the darkness worse, not better.
Other signs include crepey texture on the neck or hands, skin that looks thin and fragile, and areas where other treatments have not worked. Polynucleotides repair the skin itself, so they suit people whose concern is texture and quality rather than lines or volume. If you have been told you need under-eye filler but the skin there looks thin and dark, polynucleotides may be the better starting point. A consultation will confirm which.
Our Polynucleotide Treatment Options
Polynucleotides are injected into the skin to stimulate repair and regeneration. They use purified DNA fragments that trigger fibroblast activity, improving skin thickness, elasticity and tone. Treatment is available for the face, under-eye area, neck and body, from £180 per treatment area. The under-eye area is the most common starting point, and we have a dedicated Under-Eye Polynucleotides page for clients specifically concerned about dark hollows and crepey skin.
Treatment is a short course — typically two to three sessions spaced a few weeks apart. Results build gradually as the skin repairs itself. For overall skin quality, Skin Boosters like Jalupro, Vitaran and Nucleofill work on hydration and collagen stimulation, and they pair well with polynucleotides. Profhilo is another option that lifts and hydrates without adding volume.
The key difference between polynucleotides and filler is this: filler adds volume, polynucleotides repair skin. If your under-eye concern is hollowing caused by fat loss, filler may be right. If it is dark, thin, crepey skin, polynucleotides are the better choice. We will tell you honestly at your consultation which one you need, because getting it wrong wastes your money and can make the concern worse.
Polynucleotide Pricing
20% non-refundable deposit required. Deposit deducted from final balance. Course of 2 to 3 sessions recommended, spaced a few weeks apart. Consultation included.
Polynucleotides for Birmingham Clients
Our clinic on Swanshurst Lane in Moseley is easily reached from Kings Heath, Edgbaston, Hall Green, Bournville, Selly Oak and Harborne. Street parking is available on Swanshurst Lane with no permit needed.
Local expertise matters with polynucleotides because the diagnosis has to be right. If the concern is volume loss and you treat it with a skin repair product, you will see limited results. If the concern is thin, dark skin and you treat it with filler, you may make it worse. Hafsa Ashadu-Campbell has over 13 years of NHS clinical experience, including dermatology at Great Ormond Street Hospital, and will tell you honestly which treatment your concern needs.
What to Expect
Your appointment starts with a consultation. We assess your skin, determine whether your concern is a skin issue or a volume issue, and recommend the right treatment. The injections are shallow and quick — most people describe a mild scratch. Numbing cream is available for sensitive areas like the under-eyes.
You may have small bumps or redness for a day or two. Results build gradually over the course of two to three sessions as the skin repairs itself. The full price is published upfront, and a 20% deposit holds your appointment.
Why Choose Us for Polynucleotides
The most important thing with polynucleotides is getting the diagnosis right — skin issue or volume issue. We tell you honestly which one you have, because getting it wrong wastes your money. Every treatment includes a consultation with no obligation to book on the day. Every price is published upfront. We plan the full course with you so you know the total cost before you start. We are fully insured and will say no if a different treatment would serve you better.
Related Treatments
Skin Boosters
Hydrating biostimulators — Jalupro, Vitaran, Nucleofill, Iluma Luna — for overall skin quality.
Learn moreProfhilo
Pure hyaluronic acid that spreads through skin to lift and hydrate without changing your shape.
Learn moreUnder-Eye Polynucleotides
Targeted polynucleotide treatment for dark hollows and crepey under-eye skin.
Learn moreInjectable Treatments
Our full range of injectable treatments — anti-wrinkle, fillers, boosters and more.
Learn moreReady to Repair Your Skin?
Call 07405 696 933 or book online. Polynucleotide treatments from £180 per area, with an honest assessment of whether your concern is a skin issue or a volume issue. Consultation included. A 20% deposit holds your slot.
Looking for our full range of treatments? Visit our aesthetics clinic in Moseley to explore all services, prices and booking options.
